Astraea

AI Operating System for Clinical Development

Hiring — 1 openYC-S26Early

What Astraea does

Astraea automates clinical trial biometrics from raw study inputs to FDA-ready outputs. The platform handles data normalization, CDISC mapping, SDTM, ADaM, TFLs, QC, and revision workflows in one auditable system, helping Phase II/III sponsors reduce months of manual programming and data management into automated, reviewable execution.

1 open role

Founding Engineer
San Francisco, CA, USFull-time1+ years$120K - $220K0.50% - 2.00% equityVisa: Will sponsor
What the role involves

We are looking for a founding engineer who wants to build deeply technical AI systems in one of the most important and regulated industries in the world. You will work directly with the founders to: Build agentic workflows for clinical trial automation Design reliable systems for document ingestion, data transformation, validation, and auditability Own core product surfaces across frontend, backend, data infrastructure, and AI orchestration Work closely with clinical teams to turn messy real-world workflows into production software Ship quickly while maintaining the rigor required for regulated healthcare environments You might be a fit if you: Are an exceptional full-stack or backend engineer Care about building reliable, production-grade AI systems and can/have integrated into legacy systems in the past Move fast, take ownership, and like ambiguous technical problems Are excited by using AI to automate healthcare, clinical trials, or regulated data workflows Want to join at the earliest stage and help define the engineering culture We care less about credentials and more about raw ability, taste, speed, and ownership. This is a high-agency founding role for someone who wants to build category-defining software.

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Company facts compiled from public sources and last refreshed 9 September 2026. Details change; treat the company’s own site as the authority.

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