Founding Engineer

at Convexia — The world's first AI-maximalist pharma company

San Francisco, CA, US / RemoteFull-timeAny (new grads ok)$90K - $200K0.50% - 1.50% equityYC-S25

What the role involves

As a Founding Engineer at Convexia, you will build the core agentic frameworks and evaluation systems that power our Source → Diligence → Decide product.

Your Role

Build and iterate on agentic orchestration frameworks: Develop robust systems for tool calling, routing, memory management, guardrails, provenance tracking, and failure recovery to ensure seamless agent performance.

Design evaluation and backtesting harnesses: Create comprehensive tools for our agents and PoS model, including offline replay, regression testing, and confidence calibration to validate and refine system accuracy.

Own end-to-end product delivery: Manage the full lifecycle from data ingestion and processing to user experience and system reliability, incorporating tight feedback loops from customers to drive rapid improvements.

Enhance system performance and correctness: Tackle challenges with messy, real-world inputs like PDFs, tables, slides, non-English sources, and conflicting evidence to deliver reliable results.

Partner with founders on strategy: Collaborate on the product roadmap, customer integrations, and technical direction as we transition from a platform to owning and advancing key assets.

We’re hiring for people that are high-agency and a bit delusional. Specifically, you:

You've built and shipped complex backend or ML systems in production, with a bias toward reliability

You obsess over evaluation, observability, and failure modes

You thrive in ambiguity and move fast without waiting for permission

You communicate clearly and take ownership in low-process environments

Other things we like

  • You've been underestimated before
  • You've been told you're "too intense"
  • You get bored in the absence hard problems
  • Hacker house vibes appeal to you

About Convexia

An AI-maximalist pharma platform. We use agents to buy drugs, run clinical trials, and sell for a profit. 10x faster and 20x leaner than incumbents. Sourcing Agent: Mines public/private databases and unstructured global data to surface overlooked preclinical candidates. Scientific Agent: Runs comp bio models (ESM-3, RFdiffusion, Boltz-2, AlphaFold) to assess safety and efficacy in silico. Commercial Agent: Analyzes FDA incentives, pricing dynamics, TAM, competitive landscape, and payer alignment. Clinical Agent: Runs digital twin simulations, evaluates CRO/CMC risk, and builds trial plans to Phase 1. PoS Agent: Evaluates the most critical factors that impact the likelihood of clinical trial success. Built by 2 Stanford CS students who have built 3 startups together before.

Full Convexia profile

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